A study on influence of pranayama on high sensitivity C-reactive protein and creatinine kinase levels in chronic obstructive pulmonary disease patients
Purpose: The present study is aimed to observe the differential response of pranayama in reducing high sensitivity C-reactive protein and creatinine kinase levels among chronic obstructive pulmonary disease patients in comparison to control patients.
Material and Methods: An intervention study was done by enrolling 100 chronic obstructive pulmonary disease patients who were managed by therapeutics. The participants were divided into intervention and non-intervention group with 50 each sample. The intervention was in the form of sequenced yogic practices for 6 weeks. The pre-intervention and post-intervention inflammatory maker levels were estimated along with lung function estimation.
Results: The result was analyzed by descriptive statistics. The mean C-reactive protein, serum creatinine kinase value decreased from 9.53 to 7.85mg/L and from 145.01 to 140.57 U/L respectively following 6 weeks of yogic practices intervention. The observed values were found to be statistically significant (p=<0.05).
Conclusion: The statistically significant reduction in inflammatory makers, C-reactive protein and creatinine kinase level following 6-week yogic practices in chronic obstructive pulmonary disease patient suggests including such yogic interventions in the regular management protocols of chronic obstructive pulmonary disease patients.
Agarwal AK, Raja A, Brown BD. Chronic Obstructive Pulmonary Disease. Treasure Island (FL): StatPearls Publishing; 2021.
Geneva. World Health Organization. Chronic obstructive pulmonary disease (COPD). [Document in the Internet]; 2021. Available from: https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd).
USA. Global Initiative for Chronic Obstructive Lung Disease. World COPD Day 2021 [Document in the Internet]; 2021. Available from: https://goldcopd.org/world-copd-day/
Zeng Y, Jiang F, Chen Y, Chen P, Cai S. Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review. Int J Chronic Obstructive Pulmonary Diseases, 2018; 13: 2013-2023.
Sengupta P. Health impacts of yoga and pranayama: a state-of-the-art review. Int J Preventive Medicine, 2012; 3: 444-58.
Khanam AA, Sachdeva U, Guleria R, Deepak KK. Study of pulmonary and autonomic functions of asthma patients after yoga training. Ind J Physiol Pharmacol, 1996; 40: 318-24.
Yanbaeva DG, Dentener MA, Spruit MA, Duistermaat JJH, Kotz D, Passos VL. IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study. BMC Med Genet, 2009; 10: 23-9.
Burki NK, Diamond L. Serum creatine phosphokinase activity in asthma. Amer Rev Respr Dis, 1977; 116: 327-31.
France. The World Medical Association Ethics Unit. Declaration of Helsinki. [Document in the Internet]; 2017. Available from: http://www.wma.net/e/ethicsunit.
Bijlani RL, Manjunatha S. Yoga. In: Bijlani RL, Manjunatha S, editors. Understanding Medical Physiology: A Textbook for Medical Students. New Delhi, India: Jaypee Brothers Medical Publishers; 2011. p. 743.
Gupta A, Gupta R, Sood S, Arkham M. Pranayam for treatment of chronic obstructive pulmonary disease: results from a randomized, controlled trial. Integr Med (Encinitas), 2014; 13: 26-31.
Katiyar SK, Shailesh B. Role of pranayama in rehabilitation of COPD patients - a Randomized Controlled Study. Ind J Allergy Asthma Immunol, 2006; 20: 98-104.
Behera D. Yoga therapy in chronic bronchitis. J Asso Physc India, 1998; 46: 207-8.
Soni R, Munish K, Singh K, Singh S. Study of the effect of yoga training on diffusion capacity in chronic obstructive pulmonary disease patients: A controlled trial. Int J Yoga, 2012; 5: 123-7.
Karthik PS, Chandrasekhar M, Ambareesha K, Nikhil C. Effect of pranayama and suryanamaskar on pulmonary functions in medical students. J Clin Diagn Res, 2014; 8: BC04-6.
Shete SU, Verma A, Kulkarni DD, Bhogal RS. Effect of yoga training on inflammatory cytokines and C-reactive protein in employees of small-scale industries. J Educ Hlth Promotion, 2017; 6: 76-83.
Stephens I. Medical yoga therapy. Children (Basel), 2017; 4: 12-9.
Copyright (c) 2022 Health, sport, rehabilitation
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors published in this journal agree to the following conditions:
a. Authors reserve the copyright to the work and transfer to the journal the right of first publication along with the work, while licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of authorship of this work and a link to the original publication in this journal.
b. The authors reserve the right to conclude separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, post it in a university repository or publish it in a book), with reference to the original publication in this journal.
c. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the process of reviewing it by this journal, as this can lead to a productive discussion, as well as to more links to this published article. work (See The Effect of Open Access).